2018 CCIA Projects
A Platform Trial Design to Accelerate Translational Therapies in a Canine Disease Model of ALS
University of Missouri
Principal Investigator: Joan Ripley Coates, D.V.M., M.S., and Sarah A. Moore, D.V.M.
Grant Number: 1-R21TR002277-01A1
Collaborating Institutions: The Ohio State University, Tufts University, North Carolina State University, Voyager Therapeutics
Learn more about this project in the NIH RePORTER.
Accelerate Cellular Immunotherapy Development for Treatment of Life-Threatening Childhood Disorders
Seattle Children’s Hospital
Principal Investigator: Julie R. Park, M.D., and Bonnie W. Ramsey, M.D.
Grant Number: 1-U01TR002487-01
Collaborating Institutions: Children’s National Health System, UCSF Benioff Children’s Hospital, Children’s Hospital Los Angeles, University of Colorado Denver, Fred Hutchinson Cancer Research Center
Learn more about this project in the NIH RePORTER.
Project Website: Consortium for Pediatric Cellular Immunotherapy
Effects of apoE-Enhancing Compounds on Alzheimer’s Disease Phenotypes In Vivo
Columbia University
Principal Investigators: Tae-Wan Kim, Ph.D., and John R. Cirrito, Ph.D.
Grant Number: 1-R21TR002029-01A1
Collaborating Institution: Washington University in St. Louis
Learn more about this project in the NIH RePORTER.
Harnessing Human Brain and Liver Microphysiological Systems for Testing Therapeutics for Metastatic Melanoma
Vanderbilt University
Principal Investigator: John Peter Wikswo, Ph.D., M.S., William L. Murphy, Ph.D., M.S., and D. Lansing Taylor, Ph.D.
Grant Number: 1-U01TR002383-01
Collaborating Institutions: University of Wisconsin–Madison, University of Pittsburgh School of Medicine, AstraZeneca
Learn more about this project in the NIH RePORTER.
Harnessing the Power of CTSA-CDRN Data Networks: Using Social Determinants of Health, Frailty and Functional Status to Identify At-Risk Patients and Improve Risk Adjustment
University of Texas Health Science Center at San Antonio
Principal Investigator: Paula K. Shireman, M.D., M.S.
Grant Number: 1-U01TR002393-01
Collaborating Institutions: University of Texas at Austin, University of Texas Health Science Center at Houston, University of Pittsburgh
Learn more about this project in the NIH RePORTER.
Impact of Breast Milk on Infant Gut Microbiome
University of Rochester
Principal Investigator: Kirsi Järvinen-Seppo, M.D., Ph.D., and R. John Looney, M.D.
Grant Number: 1-R21TR002516-01
Collaborating Institutions: University of California, San Diego, Icahn School of Medicine at Mount Sinai
Learn more about this project in the NIH RePORTER.
Increasing Access to Clinical Microbiome Specimens via a Living µBiome Bank
Medical University of South Carolina
Principal Investigator: Alexander V. Alekseyenko, Ph.D.
Grant Number: 1-R21TR002513-01
Collaborating Institutions: University of Iowa, The George Washington University
Learn more about this project in the NIH RePORTER.
Project Website: Program for Human Microbiome Research
Peer-based Retention Of people who Use Drugs in Rural Research (PROUD-R2)
Oregon Health & Science University
Principal Investigator: Philip Todd Korthuis, M.D., M.P.H., and April Marie Young, Ph.D., M.P.H.
Grant Number: 1-U01TR002631-01
Collaborating Institutions: University of Kentucky Research Foundation, Emory University, University of North Carolina at Chapel Hill, The Ohio State University
Learn more about this project in the NIH RePORTER.
Project Website: PROUD-R2: The Peer-Based Retention of People who Use Drugs in Rural Research
Precision Medicine in the Diagnosis of Genetic Disorders in Neonates
Tufts Medical Center
Principal Investigator: Jonathan M. Davis, M.D., and Jill Lamanna Maron, M.D., M.P.H.
Grant Number: 1-U01TR002271-01
Collaborating Institutions: Rady Children’s Institute for Genomic Medicine, University of North Carolina at Chapel Hill, Columbia University, Icahn School of Medicine at Mount Sinai, UPMC Children’s Hospital of Pittsburgh, University of Michigan
Learn more about this project in the NIH RePORTER.
Project Website: Researchers receive NIH award to integrate genomic sequencing into neonatal diagnosis and care
TCR and BCR Deep Sequencing to Distinguish Autoimmune Recurrence from Allograft Rejection
Columbia University Health Sciences
Principal Investigator: Megan Sykes, M.D.
Grant Number: 1-R21TR002279-01
Collaborating Institution: University of Pennsylvania
Learn more about this project in the NIH RePORTER.
TEAMSS – Transforming Expanded Access to Maximize Support & Study
University of Michigan at Ann Arbor
Principal Investigator: George Alexander Mashour, M.D., and Kevin J. Weatherwax
Grant Number: 1-U01TR002488-01
Collaborating Institutions: University of Rochester, University of Texas Southwestern Medical Center, Duke University
Learn more about this project in the NIH RePORTER.
Project Website: TEAMSS Team Finds That Use of and Support for ‘Expanded Access’ is Widespread
Transforming Exercise Testing and Physical Activity Assessment in Children: New Approaches to Advance Clinical Translational Research in Child Health
University of California, Irvine
Principal Investigator: Dan M. Cooper, M.D., and Shlomit Radom-Aizik, Ph.D.
Grant Number: 1-U01TR002004-01A1
Collaborating Institutions: Ann & Robert H. Lurie Children’s Hospital of Chicago, Children’s Hospital Los Angeles
Learn more about this project in the NIH RePORTER.
Repurposing Misoprostol to Prevent Recurrence of Clostridium difficile Infection
Vanderbilt University Medical Center*
Principal Investigator: David M. Aronoff, M.D.
Grant Number: 5U01TR002398-02
Collaborating Institutions: Washington University in St. Louis; The University of North Carolina at Chapel Hill
Learn more about this project in the NIH RePORTER.
Project Website: Grant bolsters study of potential new therapy for C. diff infection
* Note: This U01 was funded by Drug Development Partnership Programs, Office of the Director, National Center for Advancing Translational Sciences.